Glimitate M1 is a combination of two antidiabetic drugs, namely: Glimepiride and Metformin. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin SR is a Sustained-release formulation that releases the drug in smaller portions over a longer duration of time. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood.

Take Glimitate M1 as prescribed by your doctor. You are advised to take GLIMEPIRIDE+METFORMIN for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects of GLIMEPIRIDE+METFORMIN do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to GLIMEPIRIDE+METFORMIN or any other medicines, please tell your doctor. GLIMEPIRIDE+METFORMIN is not recommended for children. Avoid breastfeeding while taking GLIMEPIRIDE+METFORMIN as it may be excreted in human milk.

If you are pregnant or planning for pregnancy, please inform your doctor before taking GLIMEPIRIDE+METFORMIN as it may harm the unborn baby. Avoid alcohol consumption with GLIMEPIRIDE+METFORMIN as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking GLIMEPIRIDE+METFORMIN. Take short, frequent meals and avoid prolonged fasting while taking GLIMEPIRIDE+METFORMIN.

Uses of Glimitate M1
In Type 2 diabetes mellitus
Medicinal Benefits
Glimitate M1 contains Glimepiride 1mg and Metformin 500mg used in the treatment of type 2 diabetes. Glimepiride stimulates cells in the pancreas that produce insulin which helps to remove sugar from the blood. Metformin PR is a prolonged-release formulation that releases the drug in smaller portions over a longer duration of time. Metformin reduces sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood.

DOSAGE & ADMINISTRATION:
General
Dosage should be individualized based on both effectiveness and tolerance. The combination should be given once daily (daily) with meals and should be started at a low dose. The initial recommended dose is one tablet once daily with breakfast or the first main meal of the day and gradually titrated after assessing the adequacy of the therapeutic response.
Directions for Use
Take GLIMEPIRIDE+METFORMIN as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush or break it.
Storage
Store in a cool and dry place away from sunlight

CONTRAINDICATIONS:
1. Renal disease or renal dysfunction (e.g., as suggested by serum creatinine levels 1.5 mg/dL [males], 1.4 mg/dL [females] or abnormal creatinine clearance), which may also result from conditions such as cardiovascular collapse (shock), acute myocardial infarction, and Septicaemia.
2. Congestive heart failure requiring pharmacologic treatment.
3. Known hypersensitivity to this product or any of its components.
4. Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma. Diabetic ketoacidosis should be treated with insulin.
5. Patients undergoing radiologic studies involving intravascular administration of iodinated contrast materials, because the use of such products may result in acute alteration of renal function.

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Glimitate M2 is with a combination of two antidiabetic drugs, namely: Glimepiride and Metformin. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin SR is a Sustained-release formulation that releases the drug in smaller portions over a longer duration of time. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood.

Take GLIMEPIRIDE+METFORMIN as prescribed by your doctor. You are advised to take GLIMEPIRIDE+METFORMIN for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects of GLIMEPIRIDE+METFORMIN do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to GLIMEPIRIDE+METFORMIN or any other medicines, please tell your doctor. GLIMEPIRIDE+METFORMIN is not recommended for children. Avoid breastfeeding while taking GLIMEPIRIDE+METFORMIN as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking GLIMEPIRIDE+METFORMIN as it may harm the unborn baby. Avoid alcohol consumption with GLIMEPIRIDE+METFORMIN as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking GLIMEPIRIDE+METFORMIN. Take short, frequent meals and avoid prolonged fasting while taking GLIMEPIRIDE+METFORMIN.

Uses of Glimitate M2
In Type 2 diabetes mellitus
Medicinal Benefits
Glimitate M2 contains Glimepiride 2mg and Metformin 500mg used in the treatment of type 2 diabetes. Glimepiride stimulates cells in the pancreas that produce insulin which helps to remove sugar from the blood. Metformin PR is a prolonged-release formulation that releases the drug in smaller portions over a longer duration of time. Metformin reduces sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood.
DOSAGE & ADMINISTRATION:
General
Dosage should be individualized on the basis of both effectiveness and tolerance. The combination should be given once daily (daily) with meals and should be started at a low dose. The initial recommended dose is one tablet once daily with breakfast or the first main meal of the day and gradually titrated after assessing the adequacy of the therapeutic response.

Directions for Use
Take GLIMITATE M2 as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush or break it.
Storage
Store in a cool and dry place away from sunlight

CONTRAINDICATIONS:
1. Renal disease or renal dysfunction (e.g., as suggested by serum creatinine levels 1.5 mg/dL [males], 1.4 mg/dL [females] or abnormal creatinine clearance), which may also result from condition s such as cardiovascular collapse (shock), acute myocardial infarction, and septicaemia.
2. Congestive heart failure requiring pharmacologic treatment.
3. Known hypersensitivity to this product or any of its components.
4. Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma. Diabetic ketoacidosis should be treated with insulin.
5. Patients undergoing radiologic studies involving intravascular administration of iodinated contrast materials, because the use of such products may result in acute alteration of renal function.

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GLIMITATE TRIO is a combination of three medicines, namely: Metformin, Glimepiride, and Pioglitazone. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Glimepiride acts by increasing the amount of insulin released by the pancreas. Pioglitazone works by decreasing the amount of glucose released by the liver and also by improving the sensitivity of tissues towards insulin effects.

You should take this medicine as prescribed by your doctor. You may experience side-effects of such as nausea (feeling sick), vomiting (falling sick), diarrhea, headache, stomach ache, respiratory infection, weight gain, sweating, palpitations, and vision problems. Some patients experience decline in blood sugar levels lower than normal (hypoglycemia) resulting in sweating, dizziness, headache, confusion, feeling hungry, temporary changes in vision, uneasiness, irritability, and weakness. In such cases, seek medical attention immediately.

Do not take GLIMEPIRIDE+METFORMIN+PIOGLITAZONE if you are allergic to any of its contents. Do not use this medicine if you have heart failure, bladder cancer, or diabetic ketoacidosis (a complication of diabetes). GLIMEPIRIDE+METFORMIN+PIOGLITAZONE may cause ‘lactic acidosis’ (accumulation of lactic acid in the blood), which requires immediate medical attention. The risk increases if you are previously diagnosed with kidney or liver diseases. Do not consume alcohol (risk of lactic acidosis) or fast for prolonged periods (risk of hypoglycemia). Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of GLIMITATE TRIO
In Type 2 Diabetes Mellitus
Medicinal Benefits
GLIMITATE TRIO contains Metformin, Glimepiride, and Pioglitazone. GLIMITATE TRIO is given when single or dual therapy of hypoglycemic agents is not effective in diabetes patients. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Glimepiride acts by increasing the secretion of insulin by the pancreas. Pioglitazone works by decreasing the amount of glucose released by the liver and improving insulin sensitivity in muscle and fat.
Directions for Use
Take GLIMITATE TRIO as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew, or break it.
Storage
Store in a cool and dry place away from sunlight

CONTRAINDICATIONS:
1. Renal disease or renal dysfunction (e.g., as suggested by serum creatinine levels 1.5 mg/dL [males], 1.4 mg/dL [females] or abnormal creatinine clearance), which may also result from conditions such as cardiovascular collapse (shock), acute myocardial infarction, and septicaemia.
2. Congestive heart failure requiring pharmacologic treatment.
3. Known hypersensitivity to this product or any of its components.
4. Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma. Diabetic ketoacidosis should be treated with insulin.
5. Patients undergoing radiologic studies involving intravascular administration of iodinated contrast materials, because the use of such products may result in acute alteration of renal function.

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Linatab 5mg Tablet is normally prescribed when diet and exercise alone or other medicines do not prove sufficient to control your blood sugar level. Your doctor may prescribe it alone or in combination with other diabetes medicines. It can be taken with or without food.

The dose will depend on your condition and blood sugar levels. Use it strictly as advised by your doctor. Do not stop taking the medicine unless your doctor recommends it. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of this medicine is hypoglycemia. It is important to recognize the symptoms of hypoglycemia (such as lightheadedness, sweating, dizziness, and fainting) and know how to deal with it. You can carry sugar or glucose candy and have them to control your symptoms if you experience any. It may also cause Nasopharyngitis in some people. Contact your doctor if any of these side effects do not go away or worry you.

Before taking this medicine, let your doctor know if you have ever had kidney disease, heart disease, or pancreas problems. Some other medicines you are taking may interfere with this medicine’s working. So, make sure your doctor knows about all the other medicines you are using.

Pregnant or breastfeeding women should also consult their doctor before taking it. Limit your alcohol intake while taking this medicine because it can increase your risk of developing low blood sugar levels. You may need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly.
USES OF Linatab 5 TABLET
Treatment of Type 2 diabetes mellitus
BENEFITS OF Linatab 5 TABLET
In Treatment of Type 2 diabetes mellitus
Linatab 5mg Tablet belongs to a group of medicines called DPP-4 inhibitors (or gliptins). It helps increase the amount of insulin your body produces after a meal and to stop your body from releasing too much glucose (sugar) into your blood. This way it lowers the blood glucose levels in your body. It is usually taken once a day and has relatively few common side effects.

Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, blindness, and loss of limbs. Proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with a proper program of diet and exercise will help you live a normal, healthy life. You should keep using it for as long as it is prescribed.

SIDE EFFECTS OF Linatab TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

HOW TO USE Linatab TABLET

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Linatab 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
HOW Linatab TABLET WORKS
Linatab 5mg Tablet is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and post meal sugar levels.

SAFETY ADVICE
It is unsafe to consume alcohol with Linatab 5mg Tablet.
Driving
Linatab 5mg Tablet does not usually affect your ability to drive.

Kidney
Linatab 5mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Linatab 5mg Tablet is recommended.
However, Linatab 5mg Tablet should be used with caution in patients with end-stage renal disease (ESRD) and those on dialysis.
Liver
Linatab 5mg Tablet is safe to use in patients with liver disease. No dose adjustment of Linatab 5mg Tablet is recommended. However, the use of Linatab 5mg Tablet is not recommended in patients with severe liver disease.
WHAT IF YOU FORGET TO TAKE LINATAB TABLET?

If you miss a dose of Linatab 5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Common side effects of Linatab
Nasopharyngitis (inflammation of the throat and nasal passages), Cough, Vomiting, Diarrhea, Constipation

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Take DAPANA as prescribed. Your doctor will recommend how often you take DAPANA based on your medical condition. In some cases, you may experience urinary tract infection, low blood sugar levels (hypoglycemia), peeing more than normal, skin rash, dizziness, increased thirst, and Nausea. Most of these side effects of DAPAGLIFLOZIN do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are hypersensitive to any of the components present in these medicines, please tell your doctor before taking it. DAPAGLIFLOZIN is not allowed to use in children below 18 years of age. If you are a woman who is pregnant or breastfeeding or planning to be pregnant, then tell your doctor before they prescribe this medicine to you. DAPAGLIFLOZIN, when used with diuretics, may increase the risk of dehydration, kidney problems and lower blood pressure. Let your doctor know if you are taking any other medication. Do not take or stop DAPAGLIFLOZIN if the doctor did not advise you to do so. Limit your alcohol consumption with DAPAGLIFLOZIN as alcohol may cause a rapid increase or decrease in blood sugar levels.

Uses of DAPANA

Type 2 Diabetes Mellitus
Medicinal Benefits
DAPANA contain DAPAGLIFLOZIN belongs to the anti-diabetic drug category, indicated in the treatment of type 2 diabetes or non-insulin-dependent diabetes (NIDDM). This medicine is primarily prescribed to persons whose blood sugar levels are high and not controlled by diet and exercise alone. DAPAGLIFLOZIN consists of “Dapaliflozin” a sodium-glucose cotransporter-2 (SGLT-2) inhibitor responsible for inhibiting SGLT-2 enzymes in the kidney. Thus, it prevents the reabsorption of glucose from the blood filtered through your kidney, thereby increasing the glucose excretion from your body when you urinate.
INDICATION:

Monotherapy: Dapagliflozin propanediol monohydrate is indicated for use as an adjunct to diet and exercise to improve glycemic control in adult patients with T2DM for whom metformin is inappropriate due to contraindications or intolerance.
Add-on combination: Dapagliflozin is indicated in adult patients with T2DM to improve glycemic control in combination with
• Metformin
• Sulfonylurea
• Metformin and a sulfonylurea
• Sitagliptin (alone or with metformin)
• Insulin (alone or with metformin)
Add-On Combination in Patients with Cardiovascular Risk Factors or Established Cardiovascular Disease: Dapagliflozin is indicated as an adjunct to diet, exercise, and standard-of-care therapy to reduce the risk of hospitalization for heart failure in adults with type 2 diabetes mellitus and CV risk factors or established CV disease.

Directions for Use
Take DAPAGLIFLOZIN with or without food as advised by a doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

CONTRAINDICATIONS:

History of serious hypersensitivity reaction to Dapagliflozin.
Severe renal impairment, end-stage renal disease, or dialysis.

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